Liver function test biochemistry

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Liver function test biochemistry


A series of blood tests called liver function tests, commonly referred to as liver panels or liver enzyme tests, are used to evaluate the condition and efficiency of the liver. These tests measure a range of proteins, enzymes, and other chemicals made by or impacted by the liver. 


These frequent liver function tests and their measurements are listed below:


Alanine aminotransferase (ALT): The liver is the main location of the enzyme ALT. Increased ALT levels in the blood can be an indication of liver disease or injury, such as hepatitis.


Aspartate aminotransferase (AST): The liver, heart, muscles, and other tissues all contain the enzyme AST. Although less specific to the liver than ALT, elevated AST levels in the blood may indicate liver disease. Additionally, illnesses including heart disease and muscular injuries can cause elevated AST levels.


Alkaline phosphatase (ALP): The bile ducts, bones, intestines, liver, and other tissues all contain the enzyme ALP. Increased ALP levels may be a sign of liver or bone problems. Increased ALP levels in the liver are frequently linked to obstructions such gallstones or liver tumours.


Gamma-glutamyl transferase (GGT): In addition to other organs, the liver and bile ducts contain the enzyme GGT. It is frequently used to evaluate liver health, identify bile duct issues, and identify liver disease caused by alcohol. Additionally, taking too much alcohol or taking some drugs can result in elevated GGT levels.


Total bilirubin: A yellow pigment called bilirubin is created when red blood cells are broken down. Total bilirubin levels that are elevated may be a sign of anaemia, liver illness, or clogged bile ducts.


Albumin: The liver makes the protein albumin. Low albumin levels could be a sign of chronic liver disease, malnutrition, or kidney issues.


Prothrombin time (PT) and International Normalized Ratio (INR): These tests evaluate the blood's clotting capacity. As the liver creates clotting factors, abnormal PT and INR readings may indicate liver injury or reduced liver function.


It's crucial to remember that while liver function tests might give general information about the health of the liver, they cannot diagnose any particular liver disorders. In order to identify the underlying reason of abnormal results, more testing and examination may be necessary. For help interpreting the findings and dispensing pertinent medical advice, consulting a healthcare professional is imperative.

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